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Phosphocreatine is a creatine molecule which is phosphorylated that rapidly mobilizes reserved phosphate of high energy that is found in the brain and skeleton muscles. In absence of oxygen the phosphocreatine is able to donate a phosphate molecule to ADP energy in order to transform it to high energy molecule by the name Adenosine Tri-phosphate. This process takes place after about seven seconds of a heavy muscular effort. In addition at low energy period ATP is able to make phosphocreatine out of creatine. This process is irreversible and it takes place with the aid of a number of catalysts which makes the process faster. One of the common catalyst that is used in this process is creatine kinases. The presence or absence of creatine in some fluids and tissues of the body is important in disease diagnosis. For example the presence of creatine in plasma fluid is an indication of muscle damages a condition known as myocardial infarction.
Phosphocreatine is usually generated from excess Adenosine Tri-phosphate. This process is usually carried out by the body cells at the time when the body is resting. Besides the previous role phosphocreatine is used to generate energy quickly during an activity of high intensity. Other than that generation of energy in form of ATP, phosphocreatine serves as a temporal and spatial buffer at the time when there is high concentration of Adenosine Tri-phosphate energy. Basically phosphocreatine is a high energy reserve in a number of chemical reactions. This energy is obtained from generation of different compounds from phosphate molecules which are usually donated by phosphorcreatine or Adenosine Tri-phosphate. Phosphocreatine is of great importance in tissues that experience great energy demands as a result high energy fluctuation. Muscles that are characterized by such reactions include muscle tissue and brain tissue. Phosphocreatine is formed in the liver after which it was transported through the bloodstream to muscles cells where it’s usually stored.
The reaction that involves production of energy by use of phosphocreatine is referred to as feedback reaction because excess production of the final product usually slows the whole reaction. A compound known as CPK usually acts on phosphocreatine in order for this compound to give its attached phosphate group which then joins ADP in order for Adenosine Tri-phosphate to be formed. This process is what is known as a phosphorylation reaction. For skeletal muscles to function normally during its processes like protein synthesis energy, in form of ATP is needed. A challenge comes in because ATP that is usually available is normally not enough for such processes to be successfully completed. During high energy exercise the muscles need to contrast and this cannot happen unless the energy present is sufficient. Reduced level of energies is as a resulted of depletion of the energy that was currently in the reserves. For these reason primary sources of energy are usually catabolized in order to create the needed energy.
Metabolism of phosphocreatine takes place at the time when oxygen is insufficient in order to produce minimal energy molecules. For these reason creatine is important for synthesis of energy during skeletal muscle contraction, its also important in acid base regulation as well as protein synthesis. The whole process takes place in the mitochondria cells and the energy which is generated is transported to sarcomere cells of the myofibrils which play an important function in muscle contraction. Some of the compounds which are important in this process include chloride and sodium transporters. Athletes usually rely on this process for rapid energy generation. Most of the times athletes consume glucose to help them generate fast energy. Oral consumption of phosphocreatine supplements helps in skeletal muscle contraction.